Our laboratory was established in April, 2003. At first, the goal of our laboratory was to use the near-field optics to investigate nanometer size samples. Due to the advancing in biomedical technology, we use nano-photonics to investigate bio-sample, such as cell, bacteria and DNA. Till now, our lab had developed  micro to nano scale Laser Caputure Microdissection (LCM) system to separate individual cells. Besides, we also developed non-invasive measurement of animal blood velocity using laser Doppler method. We also take part in the automation and detection methods of HPLC system, physical disable computer aided equipment and using ultrasonic to drive dolphin away during fishing etc. All in all, our projects are innovative. Dr. Chien-Ming Chen encourage students to join international conference to improve oral presentation and enlarge world vision. We also fellowship with University of Tokyo RIKEN institution, Asian Institute of Technology, Nation Taiwan University, Taipei Medical University, National Taiwan Ocean University, Shu-Te University. We also cooperate with company to accomplish projects of National Science Council and Ministry of Education. We hope to steadily, hardworking and follow the newest technology, making our lab students to be mature and dependable.